Highly waxy crude oils can cause significant operational problems such as blockage of a pipeline due to the precipitation and deposition of select wax components during the production and transportation of the crude oil. The cost of wax management is enormous and rapidly increasing because of increased oil production in deep sea areas. Wax management costs can be significantly reduced if wax deposition in pipeline can be accurately predicted. In this research, the wax deposition phenomenon was numerically investigated. The drift flux model was employed to predict the multiphase flow and the wax deposition was determined based on a convective model. This model accurately predicted the deposition rates for lab scale under laminar and turbulent flows. The wax deposition rate presented a good agreement with the results of commercial software OLGA. A comparison with an existing oil production well was performed, and good results were obtained in the impact in pressure drop due to cross section area reduction caused by progressive wax deposition on the pipe wall. The results of this work showed a good physical consistency and a reasonable agreement with the compared experimental and field data.