A granite-gneiss weathering profile is studied with the aim of achieving a better understanding of mechanical and hydraulic properties of residual soils. The site in focus is located at the city of Campo Magro, in Curitiba Metropolitan Area. The region under research lies at the border of Curitiba Basin, above 900 m of elevation, and it was heavily influenced by tectonic events that originated the basin. The geotechnical investigation comprised physical, chemical and mineralogical characterization. The soil behavior was assessed in both natural and compacted conditions. Suction and resistivity characteristic curves provide useful information for assessing the hydraulic properties. The weathering degree and suction levels influence are assessed in respect to unconfined compressive and tensile strength. The resistance properties are analyzed according five distinct weathering degrees. Consolidation tests are used for identifying yielding stress levels. Unsaturated triaxial tests with local strain measurements in both stress and strain control conditions are used to study the deformation behavior of the most weathered soil. The conclusions provide an overall assessment of the soil strength and compressibility variability, origin material influence and weathering evolution effects.