The present work is a search for the original meaning of the skepticism as thought by Sextus Empiricus. Beginning with a depuration of the common sense’s pejorative understanding around the words skeptic and skepticism, we pass to a brief history of the skepticism since the philosophers called proto-skeptics, passing through Pyrrho and his disciples, through the Academic skepticism, arriving to Sextus Empiricus and his therapeutic skepticism. Thus, we verify how different emphasis were being given to different stages of the skeptical reflection, some of then coming to disappear, others being recognized as parts of skeptical argumentative armory. Once arguing that the skepticism is a way of living, we passed to a reflection about the practical viability of living in a genuine skeptical way. We detected the origin of the main argument against the possibility of the skeptical life, the argument of the apraxía, which induces the skeptic to a self-refutation. From this point our main concern was comprehend the developments of the argument of the apraxía until David Hume, and also the developments of the skeptical defense, initially developed by Arcesilaus, against the Stoa’s philosophy until Sextus Empiricus. We think that Sextus, in his foundation of a skeptical live, had stepped forward Hume, this hypothesis once verified allowed us to rethink the accusation that the skeptic refutes himself, as well as rethink the scope of the suspension of judgment.