The Energy Efficiency Projects Managed by Demand Side (DSM), as well as all engineering design, require investment decisions that have associated uncertainties. Economic uncertainties are due to factors exogenous to the project being generally represented by stochastic fluctuations of electricity costs. The technical uncertainties are associated with internal factors such as performance of the projects on the basis of efficient technology chosen, its operation and maintenance. The decision of customers and investors in the acquisition of Energy Efficiency Projects depends on the expected return on the earnings of the energy saved, for example, the sale of this energy in the short term. This thesis investigates a new methodology which, considering the technical and economic uncertainties, performs a more comprehensive and realistic business complex scenario involving the Energy Efficiency Projects in Brazil. The methodology helps decision making considering managerial flexibility and risk assessment of specific projects. This is based on intelligent techniques for optimizing energy diagnoses associated with real options analysis and economic evaluation of Energy Efficiency Projects Managed by Demand Side (DSM), applied to the electricity sector in Brazil. The methodology is evaluated in two Energy Efficiency Projects for the end uses of lighting and Air Conditioning, in a consumer unit of the Commercial category, located in the city of Rio de Janeiro and connected to the distribution system in Medium Voltage (13.8kV). The results showed that with the application of genetic algorithms in optimization of energy diagnoses subprojects originated from a larger project could be built, maintaining or even widening the Cost vs. Value. Benefit (RCB) ratio. And in this way, contribute to the viability of alternative optimal designs that encourage the implementation of Energy Efficiency in Brazil.