Metapsychology consists of the basic nucleus of the psychoanalytical theory. According to the Freudian metapsychology, drive is only manifested, in psyche, as psychical representatives, which have two distinct natures: presentations and (quotas of) affect. The present research intends to investigate the development of the theory of the psychical representatives of the drive, being privileged the boarding of the economic point of view of Freudian metapsychology, mainly the first topical division of the psychic apparatus. Also the contribution of Green for the theory of affects is presented, as well as the conception of Laplanche concerning the primal repression and the process of psychic translation. After that, we make an inquiry of the anxiety in Freudian works, detaching the development of the psychopathological set of anxiety neurosis. Finally, a boarding of panic is made, approaching the contemporary psychopathological set of panic disease of the Freudian psychopathological set of anxiety neurosis, showing that it is also possible to develop other explanations, of a metapsychological character, for panic, without abandoning the categories used by Freud himself (for example, the notion of helplessness), but that have not been enough developed and associated to an ampler theory concerning panic. Thus, the present research aims at to contribute for the study of the, said, contemporaries psychophatologies, in special for the knowledge of the psychodynamics of panic disease. On the other hand, this work also intends to offer a systematic revision of some of the basic concepts of Freudian metapsychology, adding to the theoretical body of metapsychology, developments added by post-Freudian theoreticians.