The revaluation of Holy Scripture in the liturgical celebration was one of the great achievements regarding the reform of the rites promoted by the Second Vatican Council. From this event, both the Magisterium and theological reflection have matured this theme, including moving towards a perspective of the Word of God from the viewpoint of his sacramentality in liturgical actions. The present thesis then begins with this approach raised by the intuitions of the Constitution Sacrosanctum Concilium. In order to deepen the theme of the sacramentality of the Word, the study in question uses patristic theology, more precisely, that of Ambrose of Milan, focusing on its two renowned mystagogical works: De Sacramentis and De Mysteriis. In them, there is the use of biblical typology, whose purpose is to lead the neophytes to the mysterium experience. Ambrose s typological method seeks to demonstrate to newly baptized that God s effective word manifested in saving history continues to fulfill its mission of redeeming humanity. In light of Ambrose s post-baptismal instructions, the research sought to find theological-pastoral elements in relation to the sacramentality of the Word of God in liturgical celebrations. Ambrose s mystagogical preaching, in fact, is profoundly current and is today a source of inspiration for our communities – still in the process of receiving the Council s proposals – to make the liturgicalassembly experience of Scripture. The ambrosian contribution, in this sense, has the power to make christians discover the salvific efficacy of the Word proclaimed in the celebrations of the Church and to be able to respond to that same Word in worship and life.