Today, much is discussed about the preservation of contemporary art; it is no longer an uncommon subject for professionals in the field. However, reconciling the exercise of conservation-restoration with the characteristic modus operandi of contemporary artistic production remains a work full of complexity, since the latter has as one of its basic premises the elaboration of specific situations that, for the most part, defy the canons of the theory of knowledge production and the practice of cultural preservation. In other words: the nature of works of contemporary art call for epistemological revisions of art, its related areas – such as conservation-restoration – and, consequently, the real world itself as a constructed collectivity. In the present dissertation, the proposal is to analyze, under this approach, the importance of the transforming potential of current art and in what ways it can – or cannot – be preserved/maintained, taking as a case study the exhibition Queermuseu: cartografias da diferença na arte brasileira, its clashes and developments in space-time, which engendered a series of contributions to the discussion about the place of art and cultural preservation in society.