3D bioprinting technology has become an important resource in medical research, in the field of tissue engineering. However, although this technology has great convergence and demand for skills that Design has, the designer is far from such works. Thisthesis promotesthe investigation of the role that Design can play in researches on the use of 3D bioprinting. From the preliminary bibliographic review and understanding of tissue engineering and biomaterials topics, partnerships were formed in order to develop a series of practical experiments. From the construction of a desktop bioprinter and subsequent acquisition of a professional bioprinter, configuration, calibration and printing tests of different viscous materials were carried out for a better understanding of the printing process of biomaterials. In partnership with Dr. Ronaldo Andrade, an attempt was also made to solve the issue of practical simulation in medical training, with a view to generating physical models similar to living tissue. Through a partnership with the Grupo de Estudos do Fígado/UFRJ, and the laboratory of the Nuclear Engineering Program at COPPE/UFRJ, microtomography was used to generate virtual three-dimensional models that served as the basis for a software for visualization and 3D printing of a mouse liver. In partnership with researchers Sara Gemini and Jéssica Dornelas, it was possible to print constructs with cellular spheroids and subsequently analyze them via microscopy. In a new round of experiments, the developed bioink was improved and tested in different formulations. In addition to seeking advances in the investigated fields, this thesis seeks to show the interdisciplinary role of Design and its aggregating potential in research in the Medical and Biological Sciences areas, escaping the commonplace in which the professional is often placed.