Materials made with architected microstructures present tunable mechanical properties and can be used to obtain light structures and, at the same time, with maximum stiffness. In lattice structures, for example, the type of topology and porosity can be varied so that the material is efficiently distributed in the design domain. Due to the complex geometries of these structures, designing them using computer-aided design tools is a challenging task. In this work, a parametric modeling was developed in the Rhinoceros program using the Grasshopper extension to assist in the construction of models of lattice structures with varying truss diameters. The developed parametric modeling allows defining the topology and the diameter of the truss bars, which greatly simplifies the generation of models of porous solids. Microstructure models were generated and manufactured in polyamide 12 through selective laser sintering to assess whether it is feasible to print the trusses from the established parameters. The problem of a simply supported beam with a concentrated load at the center was solved using the topology optimization method and the density field was used to generate the variable density model. Considering the same final mass of the optimized models, models with constant density were generated and manufactured together with the models with variable density. Experimental analyzes were carried out using three-point bending tests and the results show that the solution using variable density has a large increase in stiffness when compared to solutions with uniform density.