This master thesis seeks to understand the effects and affects generated by transnational narratives and counter-narratives of HIV and AIDS, based on exponents of the emotional turn in International Relations that are dedicated to the study of the circulation of emotions, and the production of affective economies, through narratives. Starting from the understanding that narratives constituted by figures of speech, such as metaphor and metonymy, are producers of affections or emotions that materialize the surfaces of individual and collective bodies, we will analyze two sets of HIV and AIDS narratives that since the 1980s have tried to make sense of the origin of the virus and the clinical condition. In the first set, we will explore how transnational narratives constituted by metaphors and metonyms such as gay plague, pink cancer – associated to the gay community, and the 5Hs risk group (homosexuals, heroin addicts, Haitians, hemophiliacs and hookers) proliferated, and along with them circulated emotions that produced border effects, estrangement, discrimination, and exclusion. In the second set, we will explore how another affective economy, driven by counter-narratives that seek to resignify HIV and AIDS narratives, is produced by LGBTQIA+ non-governmental organizations, UNAIDS, online blogs or social communities, cinematic works, or testimonies of HIV personalities. Appearing in a context marked by more concrete information about the infection and the appearance of more effective drugs for viral control, this affective economy fights against the sedimentation of negative emotions in people living with HIV and uses narrative strategies such as the application of new terms to explain HIV and AIDS, the disassociation of metonymic terms, implying that HIV is not AIDS and AIDS is not death, and of metaphoric terms, deconstructing the idea of gay plague or pink cancer. In an attempt to weave HIV and AIDS narratives with movements of contestation and resignification of the epidemic of narratives, this research seeks to understand counter-narratives as urgent impositions of a new construction of what HIV and AIDS is that undoes border effects and produces possibilities of other affections, that bring together and connect.