The purpose of this thesis is to study the escape mechanisms in imperfection sensitive structural systems under certain dynamical loading conditions. Other objectives are to identify the parameters that control the escape phenomenon and to create some criteria capable of predicting the escape boundary and the structures stability in the control parameters space. This will allow a better understanding of the stability loss process and can serve as a basis to the integrity control and design of these structures. After a description of the phenomena that can occur in the dynamics of this class of structures, some predictive criteria, found in literature, that verify the structure stability based on the control parameters knowledge, are adapted and tested. Following is a study of the evolution of the global stability of the set of solutions measured by the basin of attraction area, and by the characteristics of its boundary. Some general expressions for the Melnikov criterion are developed, and it is shown by randomly perturbing the control parameters and the external force, that these expressions can be taken as a lower bound for the escape load, and consequently as a contribution to the development of design criteria. It is also observed that the values obtained by the escape criteria can be taken as an upper bound for the values of the escape force.