This dissertation intends to estabilish an analogy between science and psychosis, by verifying that both share a common operation of forclusion, of the subject and of Name-of-the-Father, respectively. We intend also to find in the clinical picture of psychosis orientations for the psychoanalist s position towards the scientific discourse present in today s culture. We will discuss about the scientific subject, from Koyré, as the seminal conception for the birth of the psychoanalitic subject, and then indicate what Lacan has specified as this psychoanalitic subject, approaching it to the notion of emptiness. We will reflect about the destiny that modern science reserves to the subject - as it is conceived by psychoanalysis-, that is, the subject s forclusion. This operation will be considered in regard to its incidence on psychosis, where it constitutes a possibility of organization of the world without the Father s parameter. Both the subject s and the Name-of-the-Father s foraclusion will be compared, in their similarities and discriminations, in order to put science and psychosis side to side. As an ilustration of the phenomena of the scientific discourse, we will make use of the modern-liquid society, defining dillemas, but also outlining possibilities of some intervention in culture.