Título: | HIV RISK BEHAVIORS IN HUMANS WITH ADVERSE CHILDHOOD EXPERIENCES: A SYSTEMATIC REVIEW WITH META-ANALYSIS | ||||||||||||
Autor(es): |
GUSTAVO ACELINO DE JESUS |
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Colaborador(es): |
BRENO SANVICENTE VIEIRA - Orientador |
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Catalogação: | 12/JUN/2025 | Língua(s): | ENGLISH - UNITED STATES |
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Tipo: | TEXT | Subtipo: | SENIOR PROJECT | ||||||||||
Notas: |
[pt] Todos os dados constantes dos documentos são de inteira responsabilidade de seus autores. Os dados utilizados nas descrições dos documentos estão em conformidade com os sistemas da administração da PUC-Rio. [en] All data contained in the documents are the sole responsibility of the authors. The data used in the descriptions of the documents are in conformity with the systems of the administration of PUC-Rio. |
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Referência(s): |
[en] https://www.maxwell.vrac.puc-rio.br/projetosEspeciais/TFCs/consultas/conteudo.php?strSecao=resultado&nrSeq=70983@2 |
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DOI: | https://doi.org/10.17771/PUCRio.acad.70983 | ||||||||||||
Resumo: | |||||||||||||
INTRODUCTION: To understand groups at higher risk to engage in HIV Risk Behaviors is
one of the main ways to prevent HIV. Because adverse life events (ACEs) are related to
epigenetic changes impairing cognition and increasing the likelihood of risk behaviors, the
aim of this work was to systematically review studies investigating ACEs effects in HIV Risk
Behaviors.
METHOD: Searches combining terms about ACE and HIV Risk Behaviors were done in
PubMed, Web of Science and Embase. Original papers assessing a group of individuals with
ACE and individuals with no ACE and comparing them about the frequency of HIV Risk
Behavior (i.e., infrequent condom use, multiple sexual partners and intravenous drug use)
were included. Data on each study was assessed and results were considered for any ACE and
other types of ACE more often reported. Methods were also reviewed. When it was possible
meta-analysis were made for each HIV Risk Behavior assessed for any ACE and for sexual
and physical abuses.
RESULTS: Nine studies were included. For any ACE and any HIV Risk Behavior five
papers studied this relation with two finding a significant positive relation between those
variables, for infrequent condom use two studies found a significant positive relation, for
multiple sex partners one study found a significant relation, a meta-analysis between any
ACE and multiple sex partners were significant and positive. For sexual abuse, seven papers
studied the relation with HIV Risk Behaviors. Two studies found a significant relation for
infrequent condom use, with a meta-analysis appointing a significant relation, for multiple
sex partners, no study found a significant relation, neither the meta-analysis. For physical
abuse, five papers studied this relation with HIV Risk Behaviors. One study found a
significant relation for infrequent condom use, and one study found a relation for multiple sex
partners, with a meta-analysis showing a significant relation between those variables. For
intravenous drug use we could not draw any conclusions due to the low number of studies
assessing this HIV Risk Behavior.
DISCUSSION: This review indicated that there is some evidence suggesting ACE effects in
HIV Risk Behaviors, but robustness lack of consistency due to the small number of studies
and variability in methods. More strong data can support future preventive directions
focusing on people who passed by ACEs.
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