This research seeks to expose aspects and provide reflections regarding the formations of human masses and, more specifically, to think about the particularities of the place occupied by the leadership figure in this phenomenon. To do this, we will start with a detailed exposition of what became known as masses, groups or crowds. Next, we will return to the origins of what became known as psychotherapy, taking as a starting point the work carried out by Mesmer based on his magnetic therapy; Following this path, we will address the paths and subsequent studies of the hypnotic practices of the renowned Charcot and Bernheim, to then arrive at the formulation of the Freudian clinic itself. Another primary task for this work will be the articulation of metapsychological concepts fundamental to this discussion: suggestion, hypnosis and regression. Our aim with this guide is to better understand the phenomenon of transference: from its embryonic perception in the most varied treatments, through psychoanalytic technique until reaching its understanding based on the phenomenon of the masses. We use the 1921 Freudian work, Mass Psychology and Analysis of the Self, to better develop this explanation and articulation. We chose this text because, in addition to working on these concepts, it also presents another scenario in which transference bonds are present, even if in another context and handled by another type of figure: the leader. As Freud states, the phenomenon of transference is not exclusive to psychoanalysis, so, from this reading, it becomes possible to glimpse the relationship between the individual in the mass and the leader and the way in which he uses his place of influence, from its objectives of domination and exercise of power.