This work aims to analyze the use of drugs as a way to regulate malaise in contemporary times. To this end, a research was carried out with an interdisciplinary proposal and of a theoretical nature, in which authors of different knowledge among the Human Sciences, such as Psychoanalysis, Sociology and Philosophy, and the Health Sciences are listed. With an emphasis on psychoanalysis, we cite texts by classic authors, such as, for example, the Freudians and Ferenczian s in order to make considerations about drug use and contemporaneity, dialoguing with more current authors. In the first chapter of the research, we address Public Health, we discuss Harm Reduction as a resource that helps the subject to deal with malaise, we address the increase in drug consumption during the Covid 19 pandemic and we consider the social aspects, the society of the spectacle and of performance; in the second chapter, we analyze the mechanisms of incorporation and introjection and their connection with the use of psychoactive substances, we discuss the drug s function for the subject, differentiating the modalities of use, the types of non compulsi ve use of the compulsive use of the drug addict, and more specifically, we stop to discuss the phenomenon of drug addiction in the third chapter, the contemporary instinctual expressions of the impulses of Eros and Tanatos, the subject s trauma and object relations are approached, which refer us to the dynamics of the drug object. We recognize the potential harm caused by drugs, especially depending on how it is used, and we realize the important place it occupies in the subject s psychic dynamics.