The modeling of biological materials is really important today, for the agreement of diverse practical surgical in the medicine. In the area of plastic surgery, the knowledge of the behavior of the human skin has a basic importance in the surgical processes. Since 1957, one technique in plastic surgery, known as skin expansion, has been much used. This technique has as objective the attainment of an additional amount of skin, for the use in the burned patients, breast reconstruction, removal of skin with not desired appearance is and other applications. This work has as objective supply to doctors the knowledge of the skin behavior, through a numerical and experimental analysis, when submitted to the expansion process. During the development of this work, we will show the methodology used to study the human skin and the results reached with the accompaniment of patients submitted to this type of surgical process. To reach the objective, different constitutive equations had been studied, looking for the best viscoelastic constants, to describe the behavior of the skin under expansion. In the study, we also evaluate the changes of the constants during the evolution of the expansion and the behavior of the skin in different regions of the human body. In the presented results, we find maximum errors for the constants of the adopted constitutive equation, to be in 28 percent order. Recent studies involving the human skin present errors in the order of 75 percent, for the elastic constants of the material. With the analysis of the results, we will be show to the behavior of the human skin, in vivo, in different regions of the body. The knowledge of a constitutive equation, that is, of the behavior of the stresses and strains that occur in the skin during the expansion process, will provide to the doctors the possibility to evaluate the diverse techniques used in the plastic surgery: The expansion of skin, breast reconstruction, analysis of sutures, analysis of scars, behavior of the skin during an incision, face lifting, and other applications.