This research seeks to comprehend how the Catholic university can face current challenges in order to interact with its faculty and especially with its student body according to the values present and stemming from the Gospel of Jesus Christ. The evangelizing mission of the Catholic university is discussed, specifically its current challenge in the pluralist society. The starting point is that cultural and religious pluralism is not only external but is found within the institution itself. The study is carried out in accordance with the tripartite pastoral method see-judgeact, interrelated with Ex Corde Ecclesiae, document that proposes the definition of the identity and mission of Christian faith that promotes human beings in the light of the message of the Kingdom of God, which entails Christian values, although not always named as such. Before the ascertainment of the existence of a hiatus between faith and life, it becomes necessary (and possible) for the Catholic university to have an active and dialogic campus ministry. More than a pastoral university, it should be a university in pastorality, a concept that points to a university atmosphere in which concrete attitudes are taken for the promotion and defense of the dignity of the human person, searching to live the integral and integrated Christian humanism, having solidarity as the guiding North. The evangelizing mission proposed in this research aims for the Catholic university to adopt a faithful posture to the evangelical values and, at the same time, to value and respect freedoms, religious diversity and cultural plurality, which characterize current society. The pastoral action undertaken in the university sphere constantly seeks to dialogue with the contemporary world as it has been announced by official Church documents: the document of Buga, the Ex Corde Ecclesiae, the conciliar document Gravissimum Educationis, the Document of Aparecida, among others. It reiterates the challenge presented to the present Catholic university, considering that the faithfulness to the office of evangelization is not optional, rather vital, justifying its Catholic adjective, considering the fact that the religious references in the Catholic institutions find themselves increasingly thinned, being absorbed or suffocated by the mercantilist business mentality and posture in the society where the university takes part. The Catholic adjective is equivalent to universal and necessarily remits to the Christian principles such the ones that illuminate the search for the truth about God, the human being and nature. The title Catholic is what specifies the university dynamism, distinguishing it from others.