This work is the result of the conjunction of four independent writings, which maintain between them the same leitmotiv, the psychopathology of sexual life in general, and the diagnosis of gender dysphoria in particular. It seeks to make the genealogy of the diagnostic category in the DSM, analyzing the power strategies that produced and maintain it in the role of psychiatric disorders. We discuss its function as a supporter for the transitional treatment model, as well as the long-term effects of the latter. Finally, we propose a prognosis of gender dysphoria diagnosis based on contemporary contingencies and historical precedents.