Roofing systems constitute a considerable part of the final costs of large single-storey buildings. The loads of this system are transferred to the columns from the girders. During the design process may be raised the question of what may be the best solutions for the roof supporting girders, mainly due to the large spans required. This dissertation presents a study of the structural configurations and the use of different materials for the design, manufacture and assembly of roofs of large single-storey buildings. Several designs of a model structure were developed where the type of profile of the main chords, the length of the spans, the geometry of the cross-section of the truss and the angulation of diagonals were varied. Based on the obtained results, a parametric analysis was performed focused on solutions presenting the lower structural weight of the girders. The great advantage of using multiplanar trusses is the good behavior out of plane that this type of structure offers, which can reduce costs with bracing and secondary elements. A deterministic study was also carried out in order to support decisions in choosing the best solution for the various types of large single-storey buildings studied. The preliminary results obtained indicate that the solution of concrete filled steel tubular chords in selected parts of the structure represents one of the most competitive solutions for this type of construction.