Convenience offered by information and communication technologies (ICTs) and the access to the personal computer — laptops, tablets and smartphones — have stimulated teleworking. Through the use of mobile technologies, office work is being done anywhere and anytime. The question then arises: How office workers are dealing with these interactions and diversity of places for carrying out their work? The objective of this research was to map the office transformations, caused by the ICTs usage routines, initiated with the insertion of the Internet, until the present day. We have worked with the hypothesis that the Internet and the facilities offered by ICTs have contributed to the fact that office work migrates from the conventional office environment to other alternative locations, and that this migration has influenced the relationship between personal and work life. To collect the office workers perceptions regarding the mobility of work activities, interviews and discussions were held in focus groups. The results of the applied techniques pointed to both the benefits, with the use of the mobile devices in the accomplishment of the work activities, as well as to points of worker s discomfort associated with this practice, in the professional and personal scope. This research proposes to contribute to the field of design, in the definition of design guidelines for spaces and interior design that reflect the increasing demands of society in relation to mobile work.