Technological progress in mobile computing and the Internet promotes an achievement of the futuristic vision in which users have access to data and services anytime and anywhere. However, this vision realization brings important issues to application development, because more attention is required to the communication between mobile devices and web services, especially regarding processing and data storage constraints, diversity standards and availability of services. This dissertation explores aspects of software engineering as autonomic computing, multi-agent systems and frameworks in developing applications for mobile devices, emphasizing autonomic management of web services use. Aiming the consolidation of the investigated concepts and provide a guide to facilitate the development of self-adapting applications, a framework is proposed to help in applications development for mobile computing. The development of two applications illustrates the framework appliance. The first application is a system that presents the risk of mass sliding in an area through a susceptibility calculation based on information of climate, topography and soil. The second application is part of a travel agency system that defines a travel package that best fit user needs.