The objective of this dissertation is to propose a set of sustainability indicators for higher education institutions, within the perspective of application in the PUC-Rio, particularly for the evaluation of its Environmental Agenda initiative. Within the institutional context in which this research is situated, it is assumed that this effort will provide the proper tools to measure the University sustainability, focusing on the seven items of its Environmental Agenda. The research methodology encompasses: (i) bibliographical and documental review on sustainable higher education institutions (HEI), sustainability assessment tools and indicators for sustainable HEI and normative referential at international level; (ii) design of a conceptual model as a basis for building properly sustainability indicators, within the perspective of future application in PUC-Rio; (iii) development of a case study focusing on the PUC-Rio s Environmental Agenda; and (v) formulation of conclusions and recommendations for entities involved and interested in promoting sustainable higher education institutions, particularly those from PUC-Rio. The main results can be summarized as follows: (i) a conceptual model for evaluating sustainability in PUC-Rio; and (ii) a consistent set of sustainability indicators for measuring the results of implementation of the PUC-Rio s Environmental Agenda.