Karl Löwith (1897-1973) has studied central themes in the current historiographical debate - as philosophy of history and historicism, European nihilism and crisis of modernity - as well as to the analysis of key authors for understanding of this debate - as Karl Marx, Friedrich Nietzsche, Jacob Burckhardt and Martin Heidegger. In order to bring closer to this discussion, this thesis aims to analyze the historiographical and philosophical trajectory of this author, who, known for his criticism of the modern conception of history, devised a secularization theory and proposed, in the late phase of his work, a reinterpretation of the concept of man who could translate the equal and simultaneous coexistence between history and nature as an alternative to modern ontohistoricism.