Título: | STUDY OF SODIUM AND POTASSIUM ION CHANNELS VIA STOCHASTIC DYNAMIC | |||||||
Autor: |
ANDREA DE LIMA FERREIRA |
|||||||
Colaborador(es): |
WELLES ANTONIO MARTINEZ MORGADO - Orientador ELISABETH COSTA MONTEIRO - Coorientador |
|||||||
Catalogação: | 19/AGO/2011 | Língua(s): | PORTUGUESE - BRAZIL |
|||||
Tipo: | TEXT | Subtipo: | THESIS | |||||
Notas: |
[pt] Todos os dados constantes dos documentos são de inteira responsabilidade de seus autores. Os dados utilizados nas descrições dos documentos estão em conformidade com os sistemas da administração da PUC-Rio. [en] All data contained in the documents are the sole responsibility of the authors. The data used in the descriptions of the documents are in conformity with the systems of the administration of PUC-Rio. |
|||||||
Referência(s): |
[pt] https://www.maxwell.vrac.puc-rio.br/projetosEspeciais/ETDs/consultas/conteudo.php?strSecao=resultado&nrSeq=18111&idi=1 [en] https://www.maxwell.vrac.puc-rio.br/projetosEspeciais/ETDs/consultas/conteudo.php?strSecao=resultado&nrSeq=18111&idi=2 |
|||||||
DOI: | https://doi.org/10.17771/PUCRio.acad.18111 | |||||||
Resumo: | ||||||||
This dissertation work presents an overview of ion channels for sodium
and potassium for making a relationship with the biophysical, computational
and mathematical. Studied in a qualitative way ion channels
from the point of view of statistical mechanics, more precisely, considering
the ion channel as a Markov process. The main objective of this work is
to represent the dynamics of ion channels using the random walk and develop
computer programs that simulate the operation thereof. We studied
the departure of ions from the beginning of the channel (source) and its
final arrival at a site (sink) a distance D. For the simulation of the channels
for sodium and potassium were considered for the atomic masses of related
chemicals, were not taken into account, the dynamic activation and inactivation
of the channels, as well as the cellular structure. The importance
of this work is to generalize the study of ion channels and thus seek parameters
that could differentiate them. We also consider the importance of
time, because we understand that real-time analysis is an important tool
for understanding the behavior of biological systems. Finally, the essay ends
with some simulation results of the channel for sodium and potassium to
the reader and propose some future work.
|
||||||||