This dissertation From the street to the quarantine: a study on sex work by transgender people in the context of the covid-19 pandemic has as main objective to analyze he increase in violence suffered by transsexual sex workers in the context of the covid-19 pandemic. Aiming to understand the working conditions experienced by transsexuals and the types of violence they were subjected to during the pandemic period, especially during the months when lockdown was recommended, we used a timeframe between 2020 and 2021. With a feminist, decolonial, and critical reading, we sought data from documentary and bibliographical research for a better understanding of the reality experienced by transsexual sex workers. As a methodological procedure, we analyzed the annual dossiers prepared by the National Association of Transvestites and Transsexuals (ANTRA) entitled Murders and Violence against Trans People from the last 2 (two) years, that is, the years 2020 and 2021. We understand that the of material brought comparative data for the observation of the increase in violence suffered by transsexual people in the period of the pandemic, especially among sex workers. The choice for the Dossiers was due to the difficulty in locating data about the trans population, which reveals how much this population is denied and invisibilized, as well as demonstrated the underreporting of data about this population. The research showed that the increase in violence suffered by the transgender population in the pandemic period, especially among sex workers, exposes a relationship of labor condition of extreme precariousness, informality and unemployment where the world of work determines which workers will exercise formal, informal, precarious jobs and those who will not have the possibility of selling their labor force.