Clustering plays an important role in data mining, being useful in many fields that deal with exploratory data analysis, such as information retrieval, document extraction, and image segmentation. Although they are essential in data mining applications, most clustering algorithms are adhoc methods. They have a lack of guarantee on the solution quality, which in many cases is related to a premature convergence to a local minimum of the search space. In this research, we address the problem of data clustering from an optimization perspective, where we propose a hybrid genetic algorithm to solve the Minimum Sum-of-Squares Clustering (MSSC) problem. This meta-heuristic is capable of escaping from local minima and generating near-optimal solutions to the MSSC problem. Results show that the proposed method outperformed the best current literature results - in terms of solution quality - for almost all considered sets of benchmark instances for the MSSC objective.