Immunization is defined as the investment in assets in such a way that the fixed income portfolio is immune to a change in interest rates. In the special case of pension funds, immunization seeks the distribution of the cash inflows in accordance with the outflows represented by the fund´s liabilities. The article compares distinct alternative methods of immunization against the traditional duration-matching strategy. All portfolios were obtained as a result of mathematical programming problems, where the choice of the immunization strategy led to the restrictions imposed on the evolution of the term structure of interest rates. Despite the intensive research related to this subject, there are some gaps to be filled yet, especially those concerned with the investment horizon. That is exactly the main objective of this thesis. The work provides the basis for selecting the most appropriate method for immunization and also demonstrates the superiority of the traditional duration-matching strategy, especially in the medium and long run. Moreover, it is demonstrated that there is no limit other than operational to the immunization process concerning Brazilian markets for investment horizons of less than 10 years.