The mankind is witnessing and suffering the consequences of the environment degradation, in scale and scope never seen in history. However, there is a growing concern regarding the quality and the future of the environment due to the loss of biodiversity and the definitive changes in Nature. The present research analyzes the strategy of internationalization and sustainable use of biodiversity as a competitive advantage of a Brazilian company, Natura, which has sustained a steady growth pace. Natura is well recognized also for its corporate social and environmental responsibility. The data interpretation found in this study was based on the theoretical references from the literature review, using Macedo-Soares` (2000) systemic and integrative model for strategic assessment. Following that, a strategic triangulation of methods was adopted in order to analyze the case study. The information was collected by documental investigation, perception with surveys and complementary data with guided interviews. Through the results obtained we concluded that the company, as opposed to many other companies, does not adopt alliances in the internalization process. Natura believes that the company has more to risk by choosing a bad partner than using its own capital to start business in other countries. Another important point is that although the company is very well succeeded in Brazil with direct sales, a new strategy had to be implemented in Europe to succeed in the European market. Without any doubt Europe is an excellent market for companies oriented towards sustained used of biodiversity.