A PDMS-252Cf-TOF (Time-of-Flight Plasma Desorption Mass Spectrometry) mass spectrometer was used to analyze condensed samples of pure water and mixtures of H2O:C2H2, H2O:C2H6 and H2O:N2O, at temperatures between 10 and 100 K. The ions desorbed due to the projectile impact were identified and their desorption yields determined. It is observed that the yield distributions as a function of the mass of the ions can be described by the sum of two exponentials. This result strongly suggests that two processes of aggregate formation occur: one, via direct emission of fragments from the solid and the other, via recombination of fragments in the gas phase. For pure H2O, the main desorbed aggregates are: ((H2O)nH2O+, (H2O)nH3O+, On +, (H2O)nO−, (H2O)nOH− and On −. For mixtures of ices H2O:C2H2 and H2O:C2H6, the series (C2H2)n + and (C2H6)n + are observed. For H2O:N2O, the series Nn +, (O)nN2 +, (O)nN2−, (O)nN4−, and (N2)nNO+ are the most abundant. Density Functional Theory (DFT), at the B3LYP/6-31G level, was used to calculate the molecular stability of emitted secondary molecular ions. Calculations for the C2Hm + structures (with m = 1 to 6) generated 26 stable structures. The stability curves per mass/charge obtained are compared with those obtained experimentally for the desorption yields per mass/charge for the same ions. Such methodology is used to predict the most likely conformations of the desorbed ions.