Orthopedic insoles have a niche in the industry for their development and manufacture, and they are crucial to the health of many people suffering from peripheral neuropathy. 3D printing has gained greater accessibility due to cheaper machines and raw materials, giving access to a wide audience, not only professionals, but also hobbyists. These printers can create parts that are very difficult to be manufactured using conventional methods, both due to scale and complexity, thus opening more space for the use of metamaterials in the industry, which can have characteristics that are different from any other natural element using microstructures. However, despite the excellent applicability of 3D printing prototyping, it is important to validate these small structures with finite element method. This work aims to perform a bibliographic review of development methodologies, both orthopendic insoles and microstructures to design insoles that meet the requirements of patients suffering from peripheral neuropathy and create an objective function for the allocation of microstructures to generate the ideal insole for the patient.