Acoustic, sonic or ultrasonic waves can be used for wireless telemetry as an alternative to electromagnetic systems, transferring data and energy along a channel formed by one or more layers of elastic solids or acoustic fluids. An example of this is the interrogation of passive sensors through a metallic wall. In this configuration, at least one acoustic transducer is attached to one face of the wall (external face) where electrical power supply is available. One or more transducers are also attached to its other side (internal face) where the sensors are installed. In most applications, these transducers are piezoelectric ceramics that generate and receive ultrasonic signals. Ultrasonic acoustic waves propagate along the elastic solid, transferring energy and data between both sides, which enables the power supply and interrogation of the sensors. This type of configuration can be used in applications where the use of an electrical or optical penetrator is not suitable. However, the response of piezoceramics may be affected by temperature variations and mechanical deformations of the metallic wall on which they are attached. The present work sought to quantify the influence of mechanical deformation and temperature changes on the communication between two ultrasonic piezo ceramic transducers, adhered to a metal plate by using an epoxy adhesive. The parameter used to quantify this influence was the S21 signal, which is the logarithm of the ratio between the power received from the output of the system (internal face of the wall) to the power transmitted by the input (external face of the wall). The work presents comparisons between experimental and simulated results obtained by using a finite element model developed through the commercial software COMSOL Multiphysics. In the configuration experimentally tested, two PZT-4 disks with diameter and thickness of, respectively, 25 and 2 mm were concentrically attached to both sides of a 6 mm thick, AISI 316 L stainless steel plate. Amplitudes of the S21 signal measured at the frequency where power transfer is maximized were obtained for different temperature and strain levels. Results for all of the evaluated conditions showed that the impedance matching frequency suffers little influence from temperature variations or strain in the plate on which the transducers are attached, having remained within a range from 0.988 to 0.995 MHz in all tests. As mechanical strains were applied to the metal plate, the amplitude of the S21 signal varied from -3.70 dB to -3.14 dB, from the undeformed condition to the maximum applied deformation (1250 (Micro)m/m). Regarding temperature changes, a small increase of 0.8 dB in the amplitude of the S21 signal was observed when increasing temperature from 30 C Degrees to 100 C Degrees. However, for temperatures above 100 C Degrees, the signal was found to quickly decay. None of the conditions studied in this work brought any impairment to the power transfer between the transducers, indicating that this type of communication can be a robust alternative to electrical penetrators.