The dissertation consists of three empirical essays which use historical data of stocks listed in NYSE. The first essay evaluates a portfolio selection approach based on the Markowitz optimization. Results show the portfolios have positive economic value, even after including transaction costs. The second essay compares the technique proposed in the first essay to the parametric approach. Results show the parametric approach performs worse than the modified Markowitz approach and shlightly better than the aggregated market. This suggests that exploring the covariance structure of stocks provides better results than overweighting stocks with characteristics associated to better riskreturn ratios in the past. The third essay evaluates models that forecast the cross-sectional variation in stock returns. Given the statistics used, benchmark models do not show greater forecasting power than skeptical or naive models. By using linear model combination or lasso technique on a model with several factors, I show it is possible to obtain slightly better results.