The topic of indoor air quality is of paramount importance to society due to its impact on human health and the increasing number of individuals staying in environments with no natural air circulation. This work describes the development of the system, low-cost and portable, for monitoring atmospheric quantities linked to indoor air quality, composed of sensors integrated into local units, including a remote system hosted in the cloud to store the results of measurements of these sensors. The normative and regulatory guidelines and documents related to the theme are presented, in addition to the sensing technologies used. After the development and characterization of the sensors, the units were distributed in university environments with different dynamics of use, where the spatial gradient of the atmospheric quantities was evaluated and analyzed according to the requirements for air quality published in the current regulation. With multiparametric monitoring, the heterogeneity of the distribution of the values of the quantities was identified, depending on the dynamics of occupation and ventilation conditions, especially for CO2 concentrations. This parameter exceeded the values recommended by the regulatory agency in all tests performed in the classroom, and higher values were shown to be strongly associated with the region of space closest to the occupants upper airways. The results point to the importance of continuous monitoring and at various points in a plane positioned at a strategic distance from the floor, according to the dynamics of occupation and the average position of the emission of gases by the respiratory process.