This work aims to present a comparative study of the mechanical performance and durability of concretes reinforced with discrete sisal and polypropylene macrofibers. Two cementitious matrices with different pozzolan material content were used. The both fibers were incorporated into fractions of 3 to 15 kg/m3 and were 51 mm long. Direct tensile tests were performed for the fibers, achieving equivalent stress values. For mechanical characterization of the composites, three-point flexural tests were performed under monotonic loading in accordance with the EN 14651 procedure. The behavior under cyclic loading was also investigated. To evaluate the fiber-matrix interaction, pull out tests were performed. The sisal fiber showed lower adhesion with the two matrices. All the composites with sisal and polypropylene fibers presented deflection softening behavior when subjected to flexural loads. In order to obtain similar flexural mechanical performance for both fibers, approximately twice dosage of sisal fiber was required. According to the classification proposed by fib Model Code, these fibers can partially or fully replace the conventional reinforcement at ultimate limit state. The durability of the composites was studied by accelerated aging process through wetting and drying cycles. The use of sisal fibers as reinforcement in the matrix with higher alkalinity showed degradation, while its incorporation into the matrix free of calcium hydroxide did not result in mechanical losses after the cycles. Concretes reinforced with polypropylene fibers did not present degradation caused by accelerated aging processes.