This research aims to analyze the specificities of the so-called school abandonment of girls from the public school system. Based on the dialogue with feminist, decolonial and anti-racist authors, we seek to trigger the persistence of colonial logic, essentially racist and patriarchal, in modernity/coloniality and its effects on the girls and women from subalternized classes lives. We analyze that girls failure and / or abandonment, as well as boys, are most often the product of the economic and racial inequality that structures our society. However, in the case of girls, who historically have, in the patriarchal order, their reproductive and sexual capacities as a target for control and exploitation, their withdrawal from school has peculiar reasons. They are related to the sexual division of labor, which places reproductive work and domestic work as natural and priority functions of the so-called female sex, placing any other activity in a less important place. Operating in coloniality, education can also have an important role in this process. By (re)producing discourses and practices that reinforce sexual roles, it perpetuates the idea that schooling is secondary for girls, contributing to school abandonment.