Cryogenic liquids are widely employed in several fields of human activity,such as in Medicine, Genetics Engineering, the industrial sector and for the scientific development. This way, applying the metrological controls in devices and systems used for the commercialization of cryogenic liquids is essential. In this dissertation we proposed the implementation of the metrological controls in this area, objectifying to establish the reliability and the guarantee of fair trade,without damages for the involved parts. Thus, the legal structure is supported by the valid regulamentation in the Brazilian case, that is mentioned and faced against international policies. The different measurement systems adopted nowadays are approached, for judging their adequacy and establishing minimum requests. Considering that there is not a broad regulamentaion, capable of aggregate aspects of the good practice and to heed the national reality, proposals and guidelines are presented for reaching the implementation of effective metrological controls.