In this work the use of structural control is studied to protect dynamically loaded building structures against undesirable vibration levels, which can cause human discomfort and, even more, compromise the building safety and integrity. The three types of structural control, passive, ative and hybrid, are analysed to show the advantages of hybrid control in reducing undesirable vibration levels. The chosen control mechanism is the so called tuned mass damper (TMD), due to its large application in Civil Engineering, having a great number of these devices been installed in buildings, bridges and industrial chimneys to control structural vibrations induced by wind loads. It is also verified the influence of TMD non linear stiffness on the main system behaviour. The use of multiple tuned mass dampers is studied as a possible way of improving the TMD robustness and performance. The hybrid mass damper (HMD) behaviour and efficiency comparing to the passive mass damper is analysed in detail. To calculate the control force the following control algorithms are used: classical optimum linear control, instantaneous optimum control and non-linear optimum control. A strategy to define the weighting matrices used in the instantaneous optimum control algorithm that minimizes the harmonic response amplitude is presented. Several numerical examples are presented aalong the work. The results show that the hybrid control is more efficient that the passive or active control used separately, requiring smaller forces reducing in this way the cost of the control system. The hybrid control system showed to be more efficient in reducing vibrations caused by loadings which had different frequencies from that considered on the passive control design. Moreover it was shown that hybrid control has a satisfactory perfomance when discrepancies in natural frequency occur.