In this work, a modification of the model for the simulation of diesel sprays with the presumed PDF method and tabulated chemical kinetics was developed. Through the coupling between the chemical part and the turbulent part, the effects of the spray were evaluated for the flamelet methodology. Where the textit flamelet concept treats the diffusive and transient flame as a set of one-dimensional flames, using the presumed PDF model for the evaluation of turbulent values. The validation of the model was performed with experimental data from the Sandia laboratory, in a chamber at constant volume. The validation and application of the model were conducted in different types of experimental trials: evaluation and comparison for different chemical kinetics models of n-heptane, validation of the method for the turbulence model K-epsilon in the constant volume chamber of the Sandia for non-reactive n-heptane, validation and comparison of the model for the reactive spray and model application for the study of the flame anchoring length and for the ignition delay time of n-heptane at different ambient temperatures. In general, the proposed modeling has demonstrated excellent predictive capacity for diesel spray combustion in a wide range of applications and is a highly promising candidate for other applications in diesel engines.