This research aims to investigate the possibilities of the renewal of signification processes and sense production in architecture, in the context of the complex contemporary condition. From the capitalistic dynamics of consumerism that govern the construction of contemporary cities emerges a spectacular architectonic production created to symbolize political-economical prosperity in which, frequently, art and architecture are associated in a process of cultural commodification. This process added to the crises of the modern paradigm, complicates the comprehension of the architect’s role and the possibilities for architecture today through a critical approach determining an impoverishment of the theoretical and architectural design activity, still conditioned to the traditional codes and rules of functionalism. In this context, an emphasis is placed on the importance of the displacement from the architectonic object and it s aestheticalformal aspects to the conceptual aspects of architecture, to be approached in the scope of the contemporary expanded field of culture. Since the incorporation of theoretical paradigms from linguistics and philosophy by artistic and architectural practices, in the 60 s, to approach the processes of matter and sense production that composes the cultural built environment, interdisciplinarity has become indispensable. These issues were approached in this study by analyzing the work of the North American architect Peter Eisenman and his interlocutors, in an intense dialog involving architecture, art and philosophy, with emphasis on the importance of resistance and criticism of the standards that limit our presence, experience and relationship with space, matter and time, through architecture.