This study analyzes the Catholic mystical tradition development and its theological content, considering it as continuer of the Jewish prophetic tradition and its translator aims through the use of imagination, or cataphatics analogies. We analyze the main elements of mystical thought and literature until the emergence of Religio Moderna. We show how the mystical literature found in Cardinal Cinsneros an enthusiast and promoter. His performance, editorial and academic, created an important intellectual substrate in Spain, strengthening mystical experiences. Finally, we discuss how St. Ignatius of Loyola got such intellectual legacy and understood some of their issues in the context of modernity, working as a experimenter od Eternity and a producer of meanings, a translator, expressing intimate relationship with God through the themes of individuality, the plurality of the modern world and quantifications.