This paper aims to present the main problems and challenges of hospital logistics and how the use of information technology can help the healthcare industry to minimize the impacts of these problems and challenges. The healthcare market involving manufacturers, distributors, suppliers and healthcare facilities, suffers great control of regulators to fulfill such requirements as traceability, handling, packaging, dispensing and disposal of health products. Complexities such as the difficulty of managing the lack or excess inventories, multiplicities of commercial items, packaging, specifications and presentations of medicines and compulsory control of batch manufacturing and expiry date of health inputs are large and impactful responsible for costs with supplies representing 25 per cent to 35 per cent of total operating costs of a health organization. Another major challenge of the health manager is to ensure patient safety, through processes of prescribing, dispensing and administration of drugs in a controlled, structured and safe way. Studies claim that medication errors represent the major cause of non-conformity in the hospital setting. In this context information technology presents itself as a tool to achieve the proper management of hospital logistics, minimizing the complexity and challenges of the healthcare industry, highlighting the use of barcode and radio frequency identification - RFID as one of the main tools information technology adopted by healthcare organizations seeking to conduct an effective and efficient logistics management.