Two API 5L steels grade X80 of the systems Nb-Cr and Nb-Cr-Mo, were submitted to physical simulation in order to obtain different regions of the HAZ similar to those of a multipass welding, the coarse grained heat affected zone (CGHAZ), supercritically coarse grained heat affected zone (SCCGHAZ), intercritically coarse grained heat affected zone (ICCGHAZ), subcritically coarse grained heat affected zone (SCGHAZ). The welding simulation was carried out on a Gleeble R 3800 considering two thermal cycles and different heat inputs 1.2, 2.5, 3.0 and 4,0 kJ/mm, typical of a girth weld. All HAZ zones were simulated only for 1.2 and 2.5kJ/mm. Since the ICCGHAZ is the probable weak link where a local brittle zone (LBZ) can occur, this region was simulated for all heat inputs studied. All simulated regions were subjected to traditional mechanical tests such as impact Charpy-V at -40 and -60C and microhardness Hv1kg. Metallographic analysis by optical microscopy (OM) and scanning electron microscopy (SEM) and fractography were also performed. The microstructures obtained for the different regions of the HAZ, by simulation were close to those of a real welding, however, the cooling rates obtained by simulation were slower than that obtained in a real welding. The mechanical properties and microstructure of the different regions of the HAZ for the systems NbCr and NbCrMo indicate that the microstructural and mechanical behavior of the intercritical region (ICCGHAZ) was considered to be similar to a local brittle zone (LBZ) for all conditions studied.