This work aimed to unify two methodologies of evolutionary algorithms to treat problems with or combinatorial characteristics, or numeric, on a unique algorithm with mix representation. It is an evolutionary algorithm inspired in quantum physics with mixed representation of the solutions space, called QIEABR. This algorithm is an extension of the model with binary representation of the chromosome from Jang, Han e Kin, the QIEA-B for combinatorial optimization, and numeric representation from Abs da Cruz, the QIEA-R for numerical optimizations. For purposes of exemplification of the new algorithm, we will introduce the algorithm in the context of neuro-evolution, in order to completely configure a feed forward neural network in terms of: selection of input variables; numbers of neurons in the hidden layer; all existing synaptic weights; and types of activation functions of each neuron. This purpose when applying the algorithm QIEA-BR to neuro-evolution receive the designation of QIEN-BR. QI for quantum-inspired, E for evolutive, N for neuro-evolution, and BR for binary-real representation. To evaluate the performance of QIEN-BR, we will use a total of six benchmark cases of classification, and two real cases in fields of science such as finance, biology and chemistry. Results will be compared with algorithms of other researchers and manual modeling of neural networks through performance measures. Statistical tests will be provided to elucidate the significance of results, and what we can conclude is that the algorithm QIEN-BR better performance others researchers in terms of classification prediction.