This research is about the straight relation between several disciplines and areas of knowledge, focusing its approach over concepts and processes inside the interface Design field. Design is represented in this research as a focus point involving ergonomics, accessibility and e-learning, once it analyses a model for transposing learning resources into accessible digital content for the visually challenged. The requisites embedded in guidelines and standard languages inside the contexts of web accessibility and e-learning, led the paths of this research as the knowledge of technical and formal issues in these areas have influenced decisions that impact over different levels for the implementation of an online educational solution. The support of the Instituto Benjamin Constant, a national reference in Brazil related to the matters of visually challenged people education, was fundamental to this research through the collaboration of its Laboratory of Distance Education (IBC/LED) and their interest in spreading the research and education retained in the institute through the tools offered by elearning. This partnership allowed benefits such as field studies, the comprehension of teaching methodologies and educational resources available and the opportunity to develop usability tests involving visually challenged students and an interface prototype elaborated following web accessibility and elearning guidelines. The result of this research suggests a model for transposing learning resources into accessible online courses, as well as a detailed checklist for the steps involved over the process.