The aim of this work is the degradation of ammonia present in industrial effluents by Caro`s Acid. Ammonia is considered a polluntant because of its toxicological effects in aquatic resources. Caro´s acid has been selected in the present study for the removal of ammonia because of its powerful oxidant characteristics and for it being used as a clean reagent. A sample with synthetic effluent with ammonia concentration grade of 100 mg/L was used for the experimental kinetic study conduced in batch reactor and laboratory scale for determination of the most significant variables and levels to develop a factorial design 2[3], with three variables: catalyst [Cu2+] mg/L, pH and molar ratio H2SO5:NH3. The considered response variables were the initial velocity of degradation and the ammonia removal percentage. Through statistic analysis, it was demonstrated that the most significant variables were pH and molar ratio H2SO5:NH3, and, in lower importance, the presence of the catalyst Cu2+. Caro´s acid has appeared as a possible oxidative in alkaline conditions, and was shown as an effective system in the following conditions: [Cu2+] =1mg/L; pH=9; H2SO5:NH3 = 48:1 in the staged addition, leading to residual ammonia concentration values of less than 20 mg/L in 150 min, at room temperature.