This work approaches the production of the Human and the Animal spaces. The goal is to understand those as zones of regulation and distribution of bodies, operated, especially, by the notion of subject. The first chapter presents the necessity of denaturalization of these spaces, starting with a reflection about some incorporeal references. The discourses that operate through the opposition between the Human and the Animal are questioned, as they call to a closed biological dimension in itself, to which a conscious subjectivity communicates. The second chapter will retake these questions, broadening them through an approach on the corporeal; once delineated by different modes of affection (corporeal and incorporeal kinds), the body is considered to be a land of inconstancy and transience. At this point, the debates of animal ethics and animal rights are confronted because they perpetuate subjectivities that go back to a biological Human identity. Finally, the third chapter presents a shift to the Human-Animal opposition from the notion of machine, of a machinic subjectivity crossed, both by the constitution of homogenized spheres between each other - Human and Animal, as well as their destabilization, which is made possible by the hybridization requested in the flows of difference. It is when the epistemological analysis acquire a political aesthetics. All this reflection is led by the philosophical reference of Jacques Derrida, mainly because of the philosophy of difference that his thought announces. In Derrida, difference is perceived as a movement, not an attribute in itself.