The mistagogic experience present in the sources of ecclesiastic tradition, especially in the third and fourth centuries, is a strong and decisive moment in the process of Christian Initiation. Among the Church Fathers representing the institution of catechumenate, Cyril of Jerusalem marks the mistagogic axis in his Mistagogic Catechesis. Through his homilies, Cyril of Jerusalem guides the process of Christian Initiation as a catechumenal way, in which the underlying theology raises the opening of the dynamics of the Revelation in personal and community experience, to Word revealed in the Scriptures, to the Tradition, to the Magisterium of the Church and to the requests that the society presents. In times of new configurations of human subjectivity and paradigmatic changes in society, the Christian Initiation of Adults has been experiencing a process of review and evaluation among local communities, under the guidance of the Magisterium of the Church and questions of pastoral nature. On this path, we approach the experience of Catechumenate with Adults in a local community, where we established a theological-pastoral- pedagogical dialogue on the line of participatory research. From this process of drafting between systematic theology and pastoral experience we present some contributions so that the Mistagogy identified in the guidelines of the Cyril of Jerusalem to the Church of his time can become a basis and guiding principle for the Christian Initiation with Adults in communities today. Our aim, therefore, is to motivate the mistagogic attitude in the Christian Initiation of Adults today, as a key charisma within the Church, reason not only for the Catechumenate with Adults, but also for evangelization today.