Pharmaceutical companies need to address the growing demand for bringing medicines to market in an economical way. Price pressure is increasing, and the advantages of having a buffered patent window is decreasing as generic manufacturing is on the rise. Having a pipeline of new drugs is critical, but it is also critical the ability to bring them to market in a cost effective and efficient manner. However, pharmaceutical companies can no longer solely rely on research and development and marketing to survive, but must also rely on supply chain management to deliver value. Within this context, this dissertation intends to analyze the supply chain management model of a major pharmaceutical company (GlaxoSmithkline - GSK) throughout an overview of the key characteristics of its supply chain, supply and demand management and some examples of projects implemented in Europe.