Peru is located in an area of high seismic activity known as the fire belt. Earthquakes recorded with different failure mechanisms result from the interaction between the Nazca and South-American tectonic plates. It is in this region where mining activities take place in the country, along with the construction of large civil structures, such as tailings dams, designed to store large amounts of material in the smallest possible area. In this work, the seismic behavior of a tailings dam located in Arequipa, Peru, built with the upstream method, was evaluated. In a seismic event that occurred in 2013, the dam suffered cracks in its body, settlement in the crest and small sand boils, indicating the reduction of the tailings resistance parameters due to possible dynamic liquefaction. In this research, the seismic hazard assessment was made by probabilistic methods, with the artificial design earthquake obtained by the spectral adjustment method. Pseudo-static analyzes of slope stability were performed, as well as the estimated permanent displacements and the potential of dynamic liquefaction were obtainded by simplified methods. The global seismic analysis of the tailings dam was carried out through the finite element method, considering the UBC3D-PLM constitutive model to simulate the mechanical behavior of tailings under cyclic loading.