The conditions of the inputs and the composition of burial material and its relations with paleoceanography and paleoclimate in the Southeast Brazilian Continental Margin (SEBCM) during glaciation and interglaciation has been insufficiently researched. The goal of study in this thesis is the application of organic and inorganic proxies to reconstruct the variations in the paleoenvironmental conditions in the southwestern portion of the South Atlantic. Additionally, the survey applies analytical methods and recent interpretative tools developed for the analysis of organic compounds, which were applied in an unprecedented way to samples of the region, such as the determination of (14)C-alkenones. Furthermore, the discussion of specific biomarkers in this study, such as sterols and Glycerol Dialkyl Glycerol Tetraethers (GDGTs), is done based on the oldest reconstruction of these proxies in the SEBCM region. Samples of cores collected from SEBCM were used to apply a methodology of alkenone isolation (Chapter 4) the first time. The purification methodology was efficient in adequately isolating the alkenones for isotopic analysis (14C-alquenonas), an important tool to evaluate paleoenvironmental processes. Age model from two cores was determinate and a general description of the sedimentary environment (from bulk parameters, grain size, and major elements: (percent)TOC, (percent)TN, (percent)carbonates, Ti/Ca, Fe/Ca, Ti/Al and Si/Al) showed an estimate of the differences in the overall composition of the material deposited on a transect through the southeastern Brazilian slope, which enabled an estimate of the sedimentary processes that influenced the transition between glaciation and inter-glaciation in relation to continental input. The coast distance and water column are the main driver factors (Chapter 5). The succession of ecosystems between the temporal events MIS3 to MIS1 could be observed based on the multi-biomarker approach (from records of alkenones, sterols and alcohols, n-alcohols and n-alkanes) and a depth gradient relating to the organic matter composition (Chapter 6). The temperature profile in the more external site fitted with the changes in the composition of planktonic organisms revealed an important contribution of dinoflagellates in MIS3, of diatoms during the most adverse climatic conditions (MIS2) and of coccolithophores associated to higher temperatures in the Holocene (MIS1). The terrigenous lipids input in shallower station reflected the history of vegetation cover and climate in the region, thus indicating a predominance of plants adapted to drier climates during MIS3 and MIS2 and expansion of plants of humid climates (ex. Rain forest) after the Early Holocene. The reconstruction of waters oceanography of the South Atlantic was studied based on delta18(O) and delta (13)C- foram isotopic composition, determination of the superficial and sub-superficial temperature (from U(37)k and TEX86(H) ), and the estimated salinity (from deltaD-alkenone and delta(18)O sea water) for the first time (Chapter 7). The two records provided an opportunity to investigate the differences between coastal and oceanic oceanographic history, despite their proximity. Based on the cross-slope approach was noted a circulation history gradient revealed a connection between superficial temperature and salinity and the continental climate conditions (South Atlantic Monsoon System anomalies) during glacial, Termination I and Holocene. There is evidence to suggest that this depth gradient have been controlled by hydrodynamics processes of the Shelf Waters in shelf continental break region and of the oceanic processes (Brazil Current and South Atlantic Subtropical Gyre) in the intermediate slope. At last, there are indications that the weakening of Atlantic Meridional Overturning Cell during and after Termination I can carry warmer waters to the Southeast coastal region of Brazil that a rain increase could result.